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Notch Signaling Contributes to Liver Inflammation by Regulation of Interleukin-22-Producing Cells in Hepatitis B Virus Infection

The mechanism of hepatitis B virus (HBV) induced liver inflammation is not fully elucidated. Notch signaling augmented interleukin (IL)-22 secretion in CD4(+) T cells, and Notch-IL-22 axis fine-tuned inflammatory response. We previously demonstrated a proinflammatory role of IL-22 in HBV infection....

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Detalles Bibliográficos
Autores principales:	Wei, Xin, Wang, Jiu-Ping, Hao, Chun-Qiu, Yang, Xiao-Fei, Wang, Lin-Xu, Huang, Chang-Xing, Bai, Xue-Fan, Lian, Jian-Qi, Zhang, Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065963/ https://www.ncbi.nlm.nih.gov/pubmed/27800305 http://dx.doi.org/10.3389/fcimb.2016.00132

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