Immunomodulatory Factors Galectin-9 and Interferon-Gamma Synergize to Induce Expression of Rate-Limiting Enzymes of the Kynurenine Pathway in the Mouse Hippocampus

Elevated levels of circulating pro-inflammatory cytokines are associated with symptomology of several psychiatric disorders, notably major depressive disorder. Symptomology has been linked to inflammation/cytokine-dependent induction of the Kynurenine Pathway. Galectins, like pro-inflammatory cytoki...

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Detalles Bibliográficos
Autores principales: Brooks, Alexandra K., Lawson, Marcus A., Rytych, Jennifer L., Yu, Kevin C., Janda, Tiffany M., Steelman, Andrew J., McCusker, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065983/
https://www.ncbi.nlm.nih.gov/pubmed/27799931
http://dx.doi.org/10.3389/fimmu.2016.00422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065983/
https://www.ncbi.nlm.nih.gov/pubmed/27799931
http://dx.doi.org/10.3389/fimmu.2016.00422

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