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Immunity Status of Blood Donors Regarding Toxoplasma gondii Infection in a Low-Income District of Abidjan, Côte d'Ivoire, West Africa

Background. Toxoplasmosis is a widespread cosmopolitan anthropozoonosis, which affects more than a third of the world population. Except the modes of transmission well known, Toxoplasma gondii can be transmitted during transplantation or blood transfusion. The aim of this study is to determine the p...

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Autores principales: Siransy, Liliane, Dasse, Sery Romuald, Dou Gonat, Serge Pacôme, Legbedji, Antoinette, N'guessan, Koffi, Kouacou, Patricia Ama, Yeboah, Richard, Menan, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066025/
https://www.ncbi.nlm.nih.gov/pubmed/27795962
http://dx.doi.org/10.1155/2016/6830895
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author Siransy, Liliane
Dasse, Sery Romuald
Dou Gonat, Serge Pacôme
Legbedji, Antoinette
N'guessan, Koffi
Kouacou, Patricia Ama
Yeboah, Richard
Menan, Hervé
author_facet Siransy, Liliane
Dasse, Sery Romuald
Dou Gonat, Serge Pacôme
Legbedji, Antoinette
N'guessan, Koffi
Kouacou, Patricia Ama
Yeboah, Richard
Menan, Hervé
author_sort Siransy, Liliane
collection PubMed
description Background. Toxoplasmosis is a widespread cosmopolitan anthropozoonosis, which affects more than a third of the world population. Except the modes of transmission well known, Toxoplasma gondii can be transmitted during transplantation or blood transfusion. The aim of this study is to determine the prevalence of IgG and IgM Toxoplasma gondii and to estimate the potential risk by blood products. Methods. This is a cross-sectional study on the research for Toxoplasma gondii antibodies (IgG and IgM) blood donors performed by ELISA. Results. An overall seroprevalence of Toxoplasma gondii among blood donors recruited was 67.92% (n = 72). Among these, 68 have Toxoplasma gondii IgG (64.15%), 12 Toxoplasma gondii IgM (11.32%), and 4 (3.77%) both. The risk varies between 8 for 100000 and 172 for 100000 donations. Conclusion. The need to strengthen security measures for people multitransfused, immunocompromised, and pregnant women to reduce the transmission of toxoplasmosis is important.
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spelling pubmed-50660252016-10-30 Immunity Status of Blood Donors Regarding Toxoplasma gondii Infection in a Low-Income District of Abidjan, Côte d'Ivoire, West Africa Siransy, Liliane Dasse, Sery Romuald Dou Gonat, Serge Pacôme Legbedji, Antoinette N'guessan, Koffi Kouacou, Patricia Ama Yeboah, Richard Menan, Hervé J Immunol Res Research Article Background. Toxoplasmosis is a widespread cosmopolitan anthropozoonosis, which affects more than a third of the world population. Except the modes of transmission well known, Toxoplasma gondii can be transmitted during transplantation or blood transfusion. The aim of this study is to determine the prevalence of IgG and IgM Toxoplasma gondii and to estimate the potential risk by blood products. Methods. This is a cross-sectional study on the research for Toxoplasma gondii antibodies (IgG and IgM) blood donors performed by ELISA. Results. An overall seroprevalence of Toxoplasma gondii among blood donors recruited was 67.92% (n = 72). Among these, 68 have Toxoplasma gondii IgG (64.15%), 12 Toxoplasma gondii IgM (11.32%), and 4 (3.77%) both. The risk varies between 8 for 100000 and 172 for 100000 donations. Conclusion. The need to strengthen security measures for people multitransfused, immunocompromised, and pregnant women to reduce the transmission of toxoplasmosis is important. Hindawi Publishing Corporation 2016 2016-10-03 /pmc/articles/PMC5066025/ /pubmed/27795962 http://dx.doi.org/10.1155/2016/6830895 Text en Copyright © 2016 Liliane Siransy et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Siransy, Liliane
Dasse, Sery Romuald
Dou Gonat, Serge Pacôme
Legbedji, Antoinette
N'guessan, Koffi
Kouacou, Patricia Ama
Yeboah, Richard
Menan, Hervé
Immunity Status of Blood Donors Regarding Toxoplasma gondii Infection in a Low-Income District of Abidjan, Côte d'Ivoire, West Africa
title Immunity Status of Blood Donors Regarding Toxoplasma gondii Infection in a Low-Income District of Abidjan, Côte d'Ivoire, West Africa
title_full Immunity Status of Blood Donors Regarding Toxoplasma gondii Infection in a Low-Income District of Abidjan, Côte d'Ivoire, West Africa
title_fullStr Immunity Status of Blood Donors Regarding Toxoplasma gondii Infection in a Low-Income District of Abidjan, Côte d'Ivoire, West Africa
title_full_unstemmed Immunity Status of Blood Donors Regarding Toxoplasma gondii Infection in a Low-Income District of Abidjan, Côte d'Ivoire, West Africa
title_short Immunity Status of Blood Donors Regarding Toxoplasma gondii Infection in a Low-Income District of Abidjan, Côte d'Ivoire, West Africa
title_sort immunity status of blood donors regarding toxoplasma gondii infection in a low-income district of abidjan, côte d'ivoire, west africa
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066025/
https://www.ncbi.nlm.nih.gov/pubmed/27795962
http://dx.doi.org/10.1155/2016/6830895
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