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The promise of epigenomic therapeutics in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is often viewed to arise primarily by genetic alterations. However, today we know that many aspects of the cancer phenotype require a crosstalk among these genetic alterations with epigenetic changes. Indeed, aberrant gene expression patterns, driven by epigen...

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Detalles Bibliográficos
Autores principales: Lomberk, Gwen A, Iovanna, Juan, Urrutia, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066125/
https://www.ncbi.nlm.nih.gov/pubmed/27337224
http://dx.doi.org/10.2217/epi-2015-0016