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Pancreatic fibroblasts smoothen their activities via AKT–GLI2–TGFα
Pancreatic stromal fibroblasts provide structural support. Activated fibroblasts are critical in the tumor microenvironment. In this issue of Genes & Development, Liu and colleagues (pp. 1943–1955) unravel the finding that depletion of Smoothened (Smo) in pancreatic stromal fibroblasts results i...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066234/ https://www.ncbi.nlm.nih.gov/pubmed/27664234 http://dx.doi.org/10.1101/gad.289272.116 |