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Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation
Current rescue therapies for life-threatening arrhythmias ignore the pathological electro-anatomical substrate and base their efficacy on a generalized electrical discharge. Here, we developed an all-optical platform to examine less invasive defibrillation strategies. An ultrafast wide-field macrosc...
Autores principales: | Crocini, Claudia, Ferrantini, Cecilia, Coppini, Raffaele, Scardigli, Marina, Yan, Ping, Loew, Leslie M., Smith, Godfrey, Cerbai, Elisabetta, Poggesi, Corrado, Pavone, Francesco S., Sacconi, Leonardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066272/ https://www.ncbi.nlm.nih.gov/pubmed/27748433 http://dx.doi.org/10.1038/srep35628 |
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