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Epithelial-mesenchymal transition induction is associated with augmented glucose uptake and lactate production in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a common malignancy with dismal prognosis. Metastatic spread and therapeutic resistance, the main causes of PDAC-related mortalities, are both partially underlined by the epithelial-mesenchymal transition (EMT) of PDAC cells. While the role of W...

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Detalles Bibliográficos
Autores principales: Liu, Menghan, Quek, Lake-Ee, Sultani, Ghazal, Turner, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066287/
https://www.ncbi.nlm.nih.gov/pubmed/27777765
http://dx.doi.org/10.1186/s40170-016-0160-x

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