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Epithelial-mesenchymal transition induction is associated with augmented glucose uptake and lactate production in pancreatic ductal adenocarcinoma
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a common malignancy with dismal prognosis. Metastatic spread and therapeutic resistance, the main causes of PDAC-related mortalities, are both partially underlined by the epithelial-mesenchymal transition (EMT) of PDAC cells. While the role of W...
Autores principales: | Liu, Menghan, Quek, Lake-Ee, Sultani, Ghazal, Turner, Nigel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066287/ https://www.ncbi.nlm.nih.gov/pubmed/27777765 http://dx.doi.org/10.1186/s40170-016-0160-x |
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