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Prevalence and Characteristics of Unruptured Cerebral Aneurysms in Ischemic Stroke Patients

BACKGROUND AND PURPOSE: The prevalence of unruptured cerebral aneurysms (UCAs) in ischemic stroke patients is not clearly defined. This study aimed to measure the prevalence and characteristics of UCAs in patients with acute ischemic stroke (AIS) and to compare our findings with those of the general...

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Autores principales: Kim, Ji Hwa, Suh, Sang Hyun, Chung, Joonho, Oh, Yeo-Jin, Ahn, Sung Jun, Lee, Kyung-Yul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Stroke Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066432/
https://www.ncbi.nlm.nih.gov/pubmed/27488981
http://dx.doi.org/10.5853/jos.2016.00164
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author Kim, Ji Hwa
Suh, Sang Hyun
Chung, Joonho
Oh, Yeo-Jin
Ahn, Sung Jun
Lee, Kyung-Yul
author_facet Kim, Ji Hwa
Suh, Sang Hyun
Chung, Joonho
Oh, Yeo-Jin
Ahn, Sung Jun
Lee, Kyung-Yul
author_sort Kim, Ji Hwa
collection PubMed
description BACKGROUND AND PURPOSE: The prevalence of unruptured cerebral aneurysms (UCAs) in ischemic stroke patients is not clearly defined. This study aimed to measure the prevalence and characteristics of UCAs in patients with acute ischemic stroke (AIS) and to compare our findings with those of the general population. In addition, we investigated the factors associated with cerebral aneurysms in AIS patients. METHODS: We retrospectively reviewed the brain magnetic resonance angiography images of 955 patients with AIS and 2,118 controls who had received a brain magnetic resonance angiography as part of a health check-up. We investigated the prevalence, size, location, and risk factors of the subjects in the context of UCAs. RESULTS: UCAs were found in 74 patients with AIS (7.7%) and in 79 who received a health check-up (3.7%). The prevalence of UCAs was significantly higher in the AIS group than in the health check-up group (odds ratio 2.17, 95% confidence interval 1.56-3.01). The mean aneurysm diameter was larger in the AIS group than in the health check-up group (3.75 mm vs. 3.02 mm, P=0.009). UCAs were primarily located in the internal carotid artery in both groups, and aneurysms in the middle cerebral artery were particularly common in the AIS group. According to multivariate analysis, hypertension alone was associated with an increased prevalence of UCAs in stroke patients. CONCLUSIONS: This study identified a higher prevalence and larger size of UCAs in AIS patients than in the general population. Hypertension was an independent risk factor of UCA in AIS.
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spelling pubmed-50664322016-10-25 Prevalence and Characteristics of Unruptured Cerebral Aneurysms in Ischemic Stroke Patients Kim, Ji Hwa Suh, Sang Hyun Chung, Joonho Oh, Yeo-Jin Ahn, Sung Jun Lee, Kyung-Yul J Stroke Original Article BACKGROUND AND PURPOSE: The prevalence of unruptured cerebral aneurysms (UCAs) in ischemic stroke patients is not clearly defined. This study aimed to measure the prevalence and characteristics of UCAs in patients with acute ischemic stroke (AIS) and to compare our findings with those of the general population. In addition, we investigated the factors associated with cerebral aneurysms in AIS patients. METHODS: We retrospectively reviewed the brain magnetic resonance angiography images of 955 patients with AIS and 2,118 controls who had received a brain magnetic resonance angiography as part of a health check-up. We investigated the prevalence, size, location, and risk factors of the subjects in the context of UCAs. RESULTS: UCAs were found in 74 patients with AIS (7.7%) and in 79 who received a health check-up (3.7%). The prevalence of UCAs was significantly higher in the AIS group than in the health check-up group (odds ratio 2.17, 95% confidence interval 1.56-3.01). The mean aneurysm diameter was larger in the AIS group than in the health check-up group (3.75 mm vs. 3.02 mm, P=0.009). UCAs were primarily located in the internal carotid artery in both groups, and aneurysms in the middle cerebral artery were particularly common in the AIS group. According to multivariate analysis, hypertension alone was associated with an increased prevalence of UCAs in stroke patients. CONCLUSIONS: This study identified a higher prevalence and larger size of UCAs in AIS patients than in the general population. Hypertension was an independent risk factor of UCA in AIS. Korean Stroke Society 2016-09 2016-08-04 /pmc/articles/PMC5066432/ /pubmed/27488981 http://dx.doi.org/10.5853/jos.2016.00164 Text en Copyright © 2016 Korean Stroke Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kim, Ji Hwa
Suh, Sang Hyun
Chung, Joonho
Oh, Yeo-Jin
Ahn, Sung Jun
Lee, Kyung-Yul
Prevalence and Characteristics of Unruptured Cerebral Aneurysms in Ischemic Stroke Patients
title Prevalence and Characteristics of Unruptured Cerebral Aneurysms in Ischemic Stroke Patients
title_full Prevalence and Characteristics of Unruptured Cerebral Aneurysms in Ischemic Stroke Patients
title_fullStr Prevalence and Characteristics of Unruptured Cerebral Aneurysms in Ischemic Stroke Patients
title_full_unstemmed Prevalence and Characteristics of Unruptured Cerebral Aneurysms in Ischemic Stroke Patients
title_short Prevalence and Characteristics of Unruptured Cerebral Aneurysms in Ischemic Stroke Patients
title_sort prevalence and characteristics of unruptured cerebral aneurysms in ischemic stroke patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066432/
https://www.ncbi.nlm.nih.gov/pubmed/27488981
http://dx.doi.org/10.5853/jos.2016.00164
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