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HbA(1c) measurement and relationship to incident stroke

AIMS: To determine the proportion of people with diabetes who have HbA(1c) measured, what proportion achieve an HbA(1c) level of < 58 mmol/mol (7.5%), the frequency of testing and if there was any change in HbA(1c) level in the year before and the year after an incident stroke. METHODS: This stud...

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Detalles Bibliográficos
Autores principales: Robson, R., Lacey, A. S., Luzio, S. D., Van Woerden, H., Heaven, M. L., Wani, M., Halcox, J. P. J., Castilla‐Guerra, L., Dawson, J., Hewitt, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066734/
https://www.ncbi.nlm.nih.gov/pubmed/26683404
http://dx.doi.org/10.1111/dme.13057
Descripción
Sumario:AIMS: To determine the proportion of people with diabetes who have HbA(1c) measured, what proportion achieve an HbA(1c) level of < 58 mmol/mol (7.5%), the frequency of testing and if there was any change in HbA(1c) level in the year before and the year after an incident stroke. METHODS: This study used the Secure Anonymised Information Linkage (SAIL) databank, which stores hospital data for the whole of Wales and ~ 65% of Welsh general practice records, to identify cases of stroke in patients with diabetes between 2000 and 2010. These were matched against patients with diabetes but without stroke disease. We assessed the frequency of HbA(1c) testing and change in HbA(1c) in the first year after stroke. Estimation was made of the proportion of patients achieving an HbA(1c) measurement ≤ 58 mmol/mol (7.5%). RESULTS: There were 1741 patients with diabetes and stroke. Of these, 1173 (67.4%) had their HbA(1c) checked before their stroke and 1137 (65.3%) after their stroke. In the control group of 16 838 patients with diabetes but no stroke, 8413 (49.9%) and 9288 (55.1%) had their HbA(1c) checked before and after the case‐matched stroke date, respectively. In patients with diabetes and stroke, HbA(1c) fell from 61–56 mmol/mol (7.7–7.3%) after their stroke (P < 0.001). Before the study, 55.0% of patients with stroke had an HbA(1c) ≥ 58 mmol/mol compared with 65.2% of control patients, these figures were 62.5% and 65.3% after the stroke. CONCLUSIONS: The frequency of diabetes testing was higher in patients who had experienced a stroke before and after their incident stroke compared with control patients but did not increase after their stroke. Glucose control improved significantly in the year after a stroke.