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HbA(1c) measurement and relationship to incident stroke

AIMS: To determine the proportion of people with diabetes who have HbA(1c) measured, what proportion achieve an HbA(1c) level of < 58 mmol/mol (7.5%), the frequency of testing and if there was any change in HbA(1c) level in the year before and the year after an incident stroke. METHODS: This stud...

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Autores principales: Robson, R., Lacey, A. S., Luzio, S. D., Van Woerden, H., Heaven, M. L., Wani, M., Halcox, J. P. J., Castilla‐Guerra, L., Dawson, J., Hewitt, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066734/
https://www.ncbi.nlm.nih.gov/pubmed/26683404
http://dx.doi.org/10.1111/dme.13057
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author Robson, R.
Lacey, A. S.
Luzio, S. D.
Van Woerden, H.
Heaven, M. L.
Wani, M.
Halcox, J. P. J.
Castilla‐Guerra, L.
Dawson, J.
Hewitt, J.
author_facet Robson, R.
Lacey, A. S.
Luzio, S. D.
Van Woerden, H.
Heaven, M. L.
Wani, M.
Halcox, J. P. J.
Castilla‐Guerra, L.
Dawson, J.
Hewitt, J.
author_sort Robson, R.
collection PubMed
description AIMS: To determine the proportion of people with diabetes who have HbA(1c) measured, what proportion achieve an HbA(1c) level of < 58 mmol/mol (7.5%), the frequency of testing and if there was any change in HbA(1c) level in the year before and the year after an incident stroke. METHODS: This study used the Secure Anonymised Information Linkage (SAIL) databank, which stores hospital data for the whole of Wales and ~ 65% of Welsh general practice records, to identify cases of stroke in patients with diabetes between 2000 and 2010. These were matched against patients with diabetes but without stroke disease. We assessed the frequency of HbA(1c) testing and change in HbA(1c) in the first year after stroke. Estimation was made of the proportion of patients achieving an HbA(1c) measurement ≤ 58 mmol/mol (7.5%). RESULTS: There were 1741 patients with diabetes and stroke. Of these, 1173 (67.4%) had their HbA(1c) checked before their stroke and 1137 (65.3%) after their stroke. In the control group of 16 838 patients with diabetes but no stroke, 8413 (49.9%) and 9288 (55.1%) had their HbA(1c) checked before and after the case‐matched stroke date, respectively. In patients with diabetes and stroke, HbA(1c) fell from 61–56 mmol/mol (7.7–7.3%) after their stroke (P < 0.001). Before the study, 55.0% of patients with stroke had an HbA(1c) ≥ 58 mmol/mol compared with 65.2% of control patients, these figures were 62.5% and 65.3% after the stroke. CONCLUSIONS: The frequency of diabetes testing was higher in patients who had experienced a stroke before and after their incident stroke compared with control patients but did not increase after their stroke. Glucose control improved significantly in the year after a stroke.
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spelling pubmed-50667342016-11-01 HbA(1c) measurement and relationship to incident stroke Robson, R. Lacey, A. S. Luzio, S. D. Van Woerden, H. Heaven, M. L. Wani, M. Halcox, J. P. J. Castilla‐Guerra, L. Dawson, J. Hewitt, J. Diabet Med Research Articles AIMS: To determine the proportion of people with diabetes who have HbA(1c) measured, what proportion achieve an HbA(1c) level of < 58 mmol/mol (7.5%), the frequency of testing and if there was any change in HbA(1c) level in the year before and the year after an incident stroke. METHODS: This study used the Secure Anonymised Information Linkage (SAIL) databank, which stores hospital data for the whole of Wales and ~ 65% of Welsh general practice records, to identify cases of stroke in patients with diabetes between 2000 and 2010. These were matched against patients with diabetes but without stroke disease. We assessed the frequency of HbA(1c) testing and change in HbA(1c) in the first year after stroke. Estimation was made of the proportion of patients achieving an HbA(1c) measurement ≤ 58 mmol/mol (7.5%). RESULTS: There were 1741 patients with diabetes and stroke. Of these, 1173 (67.4%) had their HbA(1c) checked before their stroke and 1137 (65.3%) after their stroke. In the control group of 16 838 patients with diabetes but no stroke, 8413 (49.9%) and 9288 (55.1%) had their HbA(1c) checked before and after the case‐matched stroke date, respectively. In patients with diabetes and stroke, HbA(1c) fell from 61–56 mmol/mol (7.7–7.3%) after their stroke (P < 0.001). Before the study, 55.0% of patients with stroke had an HbA(1c) ≥ 58 mmol/mol compared with 65.2% of control patients, these figures were 62.5% and 65.3% after the stroke. CONCLUSIONS: The frequency of diabetes testing was higher in patients who had experienced a stroke before and after their incident stroke compared with control patients but did not increase after their stroke. Glucose control improved significantly in the year after a stroke. John Wiley and Sons Inc. 2016-01-18 2016-04 /pmc/articles/PMC5066734/ /pubmed/26683404 http://dx.doi.org/10.1111/dme.13057 Text en © 2015 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Research Articles
Robson, R.
Lacey, A. S.
Luzio, S. D.
Van Woerden, H.
Heaven, M. L.
Wani, M.
Halcox, J. P. J.
Castilla‐Guerra, L.
Dawson, J.
Hewitt, J.
HbA(1c) measurement and relationship to incident stroke
title HbA(1c) measurement and relationship to incident stroke
title_full HbA(1c) measurement and relationship to incident stroke
title_fullStr HbA(1c) measurement and relationship to incident stroke
title_full_unstemmed HbA(1c) measurement and relationship to incident stroke
title_short HbA(1c) measurement and relationship to incident stroke
title_sort hba(1c) measurement and relationship to incident stroke
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066734/
https://www.ncbi.nlm.nih.gov/pubmed/26683404
http://dx.doi.org/10.1111/dme.13057
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