Cargando…

L-DOPA Oppositely Regulates Synaptic Strength and Spine Morphology in D1 and D2 Striatal Projection Neurons in Dyskinesia

Dopamine depletion in Parkinson's disease (PD) produces dendritic spine loss in striatal medium spiny neurons (MSNs) and increases their excitability. However, the synaptic changes that occur in MSNs in PD, in particular those induced by chronic L-3,4-dihydroxyphenylalanine (L-DOPA) treatment,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Suarez, Luz M, Solis, Oscar, Aguado, Carolina, Lujan, Rafael, Moratalla, Rosario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066835/ https://www.ncbi.nlm.nih.gov/pubmed/27613437 http://dx.doi.org/10.1093/cercor/bhw263

Ejemplares similares

Striatal Signaling in L-DOPA-Induced Dyskinesia: Common Mechanisms with Drug Abuse and Long Term Memory Involving D1 Dopamine Receptor Stimulation
por: Murer, Mario Gustavo, et al.
Publicado: (2011)

D2R signaling in striatal spiny neurons modulates L-DOPA induced dyskinesia
por: Florio, Ermanno, et al.
Publicado: (2022)

Striatal Plasticity in L-DOPA- and Graft-Induced Dyskinesia; The Common Link?
por: Rylander Ottosson, Daniella, et al.
Publicado: (2016)

Maladaptive Synaptic Plasticity in L-DOPA-Induced Dyskinesia
por: Wang, Qiang, et al.
Publicado: (2016)

Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia
por: Fieblinger, Tim, et al.
Publicado: (2014)

Genetic enhancement of Ras-ERK pathway does not aggravate L-DOPA-induced dyskinesia in mice but prevents the decrease induced by lovastatin
por: Ruiz-DeDiego, Irene, et al.
Publicado: (2018)

Untangling Cortico-Striatal Connectivity and Cross-Frequency Coupling in L-DOPA-Induced Dyskinesia
por: Belić, Jovana J., et al.
Publicado: (2016)

L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission
por: Feyder, Michael, et al.
Publicado: (2011)

Enhanced histamine H2 excitation of striatal cholinergic interneurons in L-DOPA-induced dyskinesia
por: Lim, Sean Austin O., et al.
Publicado: (2015)

Rapamycin, by Inhibiting mTORC1 Signaling, Prevents the Loss of Striatal Bidirectional Synaptic Plasticity in a Rat Model of L-DOPA-Induced Dyskinesia
por: Calabrese, Valeria, et al.
Publicado: (2020)

l-DOPA-induced Dyskinesia is Associated with Regional Increase of Striatal Dynorphin Peptides as Elucidated by Imaging Mass Spectrometry
por: Hanrieder, Jörg, et al.
Publicado: (2011)

Dynamic Involvement of Striatal NG2-glia in L-DOPA Induced Dyskinesia in Parkinsonian Rats: Effects of Doxycycline
por: Nascimento, G.C., et al.
Publicado: (2023)

Dopamine D3 Receptor Plasticity in Parkinson’s Disease and L-DOPA-Induced Dyskinesia
por: Lanza, Kathryn, et al.
Publicado: (2021)

Rhes, a striatal–enriched small G–protein, mediates mTOR signaling and L–DOPA–induced dyskinesia
por: Subramaniam, Srinivasa, et al.
Publicado: (2011)

Opioid system in L-DOPA-induced dyskinesia
por: Pan, Jing, et al.
Publicado: (2017)

The Multimodal Serotonergic Agent Vilazodone Inhibits L-DOPA-Induced Gene Regulation in Striatal Projection Neurons and Associated Dyskinesia in an Animal Model of Parkinson’s Disease
por: Altwal, Feras, et al.
Publicado: (2020)

On the neuronal circuitry mediating l-DOPA-induced dyskinesia
por: Cenci, M. Angela, et al.
Publicado: (2018)

Predictors of Levo-dopa induced Dyskinesias in Parkinson's Disease
por: Athulya, RT, et al.
Publicado: (2020)

Circuit Mechanisms of L-DOPA-Induced Dyskinesia (LID)
por: Yang, Kai, et al.
Publicado: (2021)

The Dopamine D5 receptor contributes to activation of cholinergic interneurons during L-DOPA induced dyskinesia
por: Castello, Julia, et al.
Publicado: (2020)

Dopamine-Depleted Dopamine Transporter Knockout (DDD) Mice: Dyskinesia with L-DOPA and Dopamine D1 Agonists
por: Pogorelov, Vladimir M., et al.
Publicado: (2023)

Hyperactive Response of Direct Pathway Striatal Projection Neurons to L-dopa and D1 Agonism in Freely Moving Parkinsonian Mice
por: Sagot, Ben, et al.
Publicado: (2018)

Corticostriatal Plastic Changes in Experimental L-DOPA-Induced Dyskinesia
por: Ghiglieri, Veronica, et al.
Publicado: (2012)

Propranolol Relieves L-Dopa-Induced Dyskinesia in Parkinsonian Mice
por: Shi, Ziqing, et al.
Publicado: (2020)

Pathophysiological Mechanisms and Experimental Pharmacotherapy for L-Dopa-Induced Dyskinesia
por: Fabbrini, Andrea, et al.
Publicado: (2021)

Striatal Astrocytes Act as a Reservoir for L-DOPA
por: Asanuma, Masato, et al.
Publicado: (2014)

The Role of the Subthalamic Nucleus in L-DOPA Induced Dyskinesia in 6-Hydroxydopamine Lesioned Rats
por: Aristieta, Asier, et al.
Publicado: (2012)

mGlu5, Dopamine D(2) and Adenosine A(2A) Receptors in L-DOPA-induced Dyskinesias
por: Morin, Nicolas, et al.
Publicado: (2016)

Publisher Correction: The Dopamine D5 receptor contributes to activation of cholinergic interneurons during L-DOPA induced dyskinesia
por: Castello, Julia, et al.
Publicado: (2020)

L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum
por: Porras, Gregory, et al.
Publicado: (2014)

Inhaling xenon ameliorates l‐dopa‐induced dyskinesia in experimental parkinsonism
por: Baufreton, Jérôme, et al.
Publicado: (2018)

Involvement of the bed nucleus of the stria terminalis in L-Dopa induced dyskinesia
por: Bastide, Matthieu F., et al.
Publicado: (2017)

Striatal Glutamate Release in l-DOPA-Induced Dyskinetic Animals
por: Nevalainen, Nina, et al.
Publicado: (2013)

Adenosine A(2A) Receptors in Striatal Glutamatergic Terminals and GABAergic Neurons Oppositely Modulate Psychostimulant Action and DARPP-32 Phosphorylation
por: Shen, Hai-Ying, et al.
Publicado: (2013)

Targeting the D1-N-methyl-d-aspartate receptor complex reduces l-dopa-induced dyskinesia in 6-hydroxydopamine-lesioned Parkinson’s rats
por: Song, Lu, et al.
Publicado: (2016)

Distinctive Effects of D1 and D2 Receptor Agonists on Cortico-Basal Ganglia Oscillations in a Rodent Model of L-DOPA-Induced Dyskinesia
por: Skovgård, Katrine, et al.
Publicado: (2022)

β-arrestin2 alleviates L-dopa–induced dyskinesia via lower D1R activity in Parkinson’s rats
por: Zhang, Xing-Ru, et al.
Publicado: (2019)

Striatal D(1) Dopamine Neuronal Population Dynamics in a Rat Model of Levodopa-Induced Dyskinesia
por: Gao, Shasha, et al.
Publicado: (2022)

Axon terminal hypertrophy of striatal projection neurons with levodopa-induced dyskinesia priming
por: Nakamura, Takashi, et al.
Publicado: (2023)

Imbalanced Dopaminergic Transmission Mediated by Serotonergic Neurons in L-DOPA-Induced Dyskinesia
por: Navailles, Sylvia, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_atmsekkqe5pq5ccc7h87frftkf