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Usefulness of measuring renal papillae in Hounsfield units in stone - forming patients

INTRODUCTION: The aim of this work is to study the density of the renal papillae in stone-forming patients and to determine its usefulness. MATERIALS AND METHODS: This study included a total of 79 patients diagnosed with renal stones and on whom a computed tomography without contrast was performed f...

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Autores principales: Arrabal-Polo, Miguel Angel, Cano-Garcia, Maria del Carmen, Huerta-Brunel, Juan Esteban, Hidalgo-Agullo, Guillermo, Roletto-Salmo, Luis, Arrabal-Martín, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Urologia 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066894/
https://www.ncbi.nlm.nih.gov/pubmed/27622277
http://dx.doi.org/10.1590/S1677-5538.IBJU.2015.0686
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author Arrabal-Polo, Miguel Angel
Cano-Garcia, Maria del Carmen
Huerta-Brunel, Juan Esteban
Hidalgo-Agullo, Guillermo
Roletto-Salmo, Luis
Arrabal-Martín, Miguel
author_facet Arrabal-Polo, Miguel Angel
Cano-Garcia, Maria del Carmen
Huerta-Brunel, Juan Esteban
Hidalgo-Agullo, Guillermo
Roletto-Salmo, Luis
Arrabal-Martín, Miguel
author_sort Arrabal-Polo, Miguel Angel
collection PubMed
description INTRODUCTION: The aim of this work is to study the density of the renal papillae in stone-forming patients and to determine its usefulness. MATERIALS AND METHODS: This study included a total of 79 patients diagnosed with renal stones and on whom a computed tomography without contrast was performed from June 2014 to May 2015. The patients were divided into two groups: Group 1 (single episode) included 43 patients, and Group 2 (recurrent episodes) included 36 patients. The density of six renal papillae (3 per kidney) was measured, and the means obtained were compared between Groups 1 and 2. Statistical analysis was performed using SPSS 20.0. RESULTS: The mean papillary density in Group 1 was 32.26 (SD 4.07) HU compared to 42.36 (SD 8.03) HU in Group 2 (P=00001). A ROC curve was constructed, obtaining an optimal cut-off point of 36.8HU [area under the curve, 0.881 (95% CI; 0.804-0.958); P=0001], with a sensitivity of 80% and a specificity of 90%. The relative risk was estimated at 40.3 (95% CI; 10.8-151.1), meaning that a patient with a mean papillary density greater than 36.8HU would have a 40 times greater risk of having recurrent renal stones. The positive predictive value (PPV) was 81% and the negative predictive value (NPV) was 90%. CONCLUSION: The measurement of renal papillary density could be useful in predicting recurrent stone-formers. These results need to be confirmed in future studies with a greater number of patients and a longer follow-up.
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spelling pubmed-50668942016-10-20 Usefulness of measuring renal papillae in Hounsfield units in stone - forming patients Arrabal-Polo, Miguel Angel Cano-Garcia, Maria del Carmen Huerta-Brunel, Juan Esteban Hidalgo-Agullo, Guillermo Roletto-Salmo, Luis Arrabal-Martín, Miguel Int Braz J Urol Original Article INTRODUCTION: The aim of this work is to study the density of the renal papillae in stone-forming patients and to determine its usefulness. MATERIALS AND METHODS: This study included a total of 79 patients diagnosed with renal stones and on whom a computed tomography without contrast was performed from June 2014 to May 2015. The patients were divided into two groups: Group 1 (single episode) included 43 patients, and Group 2 (recurrent episodes) included 36 patients. The density of six renal papillae (3 per kidney) was measured, and the means obtained were compared between Groups 1 and 2. Statistical analysis was performed using SPSS 20.0. RESULTS: The mean papillary density in Group 1 was 32.26 (SD 4.07) HU compared to 42.36 (SD 8.03) HU in Group 2 (P=00001). A ROC curve was constructed, obtaining an optimal cut-off point of 36.8HU [area under the curve, 0.881 (95% CI; 0.804-0.958); P=0001], with a sensitivity of 80% and a specificity of 90%. The relative risk was estimated at 40.3 (95% CI; 10.8-151.1), meaning that a patient with a mean papillary density greater than 36.8HU would have a 40 times greater risk of having recurrent renal stones. The positive predictive value (PPV) was 81% and the negative predictive value (NPV) was 90%. CONCLUSION: The measurement of renal papillary density could be useful in predicting recurrent stone-formers. These results need to be confirmed in future studies with a greater number of patients and a longer follow-up. Sociedade Brasileira de Urologia 2016 /pmc/articles/PMC5066894/ /pubmed/27622277 http://dx.doi.org/10.1590/S1677-5538.IBJU.2015.0686 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Arrabal-Polo, Miguel Angel
Cano-Garcia, Maria del Carmen
Huerta-Brunel, Juan Esteban
Hidalgo-Agullo, Guillermo
Roletto-Salmo, Luis
Arrabal-Martín, Miguel
Usefulness of measuring renal papillae in Hounsfield units in stone - forming patients
title Usefulness of measuring renal papillae in Hounsfield units in stone - forming patients
title_full Usefulness of measuring renal papillae in Hounsfield units in stone - forming patients
title_fullStr Usefulness of measuring renal papillae in Hounsfield units in stone - forming patients
title_full_unstemmed Usefulness of measuring renal papillae in Hounsfield units in stone - forming patients
title_short Usefulness of measuring renal papillae in Hounsfield units in stone - forming patients
title_sort usefulness of measuring renal papillae in hounsfield units in stone - forming patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066894/
https://www.ncbi.nlm.nih.gov/pubmed/27622277
http://dx.doi.org/10.1590/S1677-5538.IBJU.2015.0686
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