A case of rhino-orbital mucormycosis in diabetes with haematogenous cerebral spread

We document the first case of haematogenous cerebral spread in Rhizopus arrhizus rhino-orbital mucormycosis, and of posaconazole related adrenal insufficiency. A patient presenting with diabetic ketoacidosis and sinusitis was treated with right medial maxillectomy, ethmoidectomy and IV liposomal amp...

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Detalles Bibliográficos
Autores principales: Snaith, Jennifer, Burns, Kharis, Kok, Jen, Chen, Sharon, Cheung, N.Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067095/
https://www.ncbi.nlm.nih.gov/pubmed/27766196
http://dx.doi.org/10.1016/j.mmcr.2016.10.002
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author Snaith, Jennifer
Burns, Kharis
Kok, Jen
Chen, Sharon
Cheung, N.Wah
author_facet Snaith, Jennifer
Burns, Kharis
Kok, Jen
Chen, Sharon
Cheung, N.Wah
author_sort Snaith, Jennifer
collection PubMed
description We document the first case of haematogenous cerebral spread in Rhizopus arrhizus rhino-orbital mucormycosis, and of posaconazole related adrenal insufficiency. A patient presenting with diabetic ketoacidosis and sinusitis was treated with right medial maxillectomy, ethmoidectomy and IV liposomal amphotericin. Orbital exenteration was performed after intraorbital spread of infection. IV caspofungin and posaconazole was added but complicated by adrenal insufficiency. MRI revealed a new left lentiform nucleus and thalamus rim-enhancing lesion indicating haematogenous cerebral spread.
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spelling pubmed-50670952016-10-20 A case of rhino-orbital mucormycosis in diabetes with haematogenous cerebral spread Snaith, Jennifer Burns, Kharis Kok, Jen Chen, Sharon Cheung, N.Wah Med Mycol Case Rep Case Report We document the first case of haematogenous cerebral spread in Rhizopus arrhizus rhino-orbital mucormycosis, and of posaconazole related adrenal insufficiency. A patient presenting with diabetic ketoacidosis and sinusitis was treated with right medial maxillectomy, ethmoidectomy and IV liposomal amphotericin. Orbital exenteration was performed after intraorbital spread of infection. IV caspofungin and posaconazole was added but complicated by adrenal insufficiency. MRI revealed a new left lentiform nucleus and thalamus rim-enhancing lesion indicating haematogenous cerebral spread. Elsevier 2016-10-06 /pmc/articles/PMC5067095/ /pubmed/27766196 http://dx.doi.org/10.1016/j.mmcr.2016.10.002 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Snaith, Jennifer
Burns, Kharis
Kok, Jen
Chen, Sharon
Cheung, N.Wah
A case of rhino-orbital mucormycosis in diabetes with haematogenous cerebral spread
title A case of rhino-orbital mucormycosis in diabetes with haematogenous cerebral spread
title_full A case of rhino-orbital mucormycosis in diabetes with haematogenous cerebral spread
title_fullStr A case of rhino-orbital mucormycosis in diabetes with haematogenous cerebral spread
title_full_unstemmed A case of rhino-orbital mucormycosis in diabetes with haematogenous cerebral spread
title_short A case of rhino-orbital mucormycosis in diabetes with haematogenous cerebral spread
title_sort case of rhino-orbital mucormycosis in diabetes with haematogenous cerebral spread
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067095/
https://www.ncbi.nlm.nih.gov/pubmed/27766196
http://dx.doi.org/10.1016/j.mmcr.2016.10.002
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