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Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts
Aging is a major risk factor in many forms of late-onset neurodegenerative disorders. The ability to recapitulate age-related characteristics of human neurons in culture will offer unprecedented opportunities to study the biological processes underlying neuronal aging. Here, we show that using a rec...
Autores principales: | Huh, Christine J, Zhang, Bo, Victor, Matheus B, Dahiya, Sonika, Batista, Luis FZ, Horvath, Steve, Yoo, Andrew S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067114/ https://www.ncbi.nlm.nih.gov/pubmed/27644593 http://dx.doi.org/10.7554/eLife.18648 |
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