TP53 drives invasion through expression of its Δ133p53β variant

TP53 is conventionally thought to prevent cancer formation and progression to metastasis, while mutant TP53 has transforming activities. However, in the clinic, TP53 mutation status does not accurately predict cancer progression. Here we report, based on clinical analysis corroborated with experimen...

Descripción completa

Detalles Bibliográficos
Autores principales: Gadea, Gilles, Arsic, Nikola, Fernandes, Kenneth, Diot, Alexandra, Joruiz, Sébastien M, Abdallah, Samer, Meuray, Valerie, Vinot, Stéphanie, Anguille, Christelle, Remenyi, Judit, Khoury, Marie P, Quinlan, Philip R, Purdie, Colin A, Jordan, Lee B, Fuller-Pace, Frances V, de Toledo, Marion, Cren, Maïlys, Thompson, Alastair M, Bourdon, Jean-Christophe, Roux, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067115/
https://www.ncbi.nlm.nih.gov/pubmed/27630122
http://dx.doi.org/10.7554/eLife.14734

Ejemplares similares

Ejemplares similares