Loss of Dendritic Complexity Precedes Neurodegeneration in a Mouse Model with Disrupted Mitochondrial Distribution in Mature Dendrites

Correct mitochondrial distribution is critical for satisfying local energy demands and calcium buffering requirements and supporting key cellular processes. The mitochondrially targeted proteins Miro1 and Miro2 are important components of the mitochondrial transport machinery, but their specific rol...

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Detalles Bibliográficos
Autores principales: López-Doménech, Guillermo, Higgs, Nathalie F., Vaccaro, Victoria, Roš, Hana, Arancibia-Cárcamo, I. Lorena, MacAskill, Andrew F., Kittler, Josef T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067282/
https://www.ncbi.nlm.nih.gov/pubmed/27705781
http://dx.doi.org/10.1016/j.celrep.2016.09.004

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