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Large Gliadin Peptides Detected in the Pancreas of NOD and Healthy Mice following Oral Administration
Gluten promotes type 1 diabetes in nonobese diabetic (NOD) mice and likely also in humans. In NOD mice and in non-diabetes-prone mice, it induces inflammation in the pancreatic lymph nodes, suggesting that gluten can initiate inflammation locally. Further, gliadin fragments stimulate insulin secreti...
Autores principales: | Bruun, Susanne W., Josefsen, Knud, Tanassi, Julia T., Marek, Aleš, Pedersen, Martin H. F., Sidenius, Ulrik, Haupt-Jorgensen, Martin, Antvorskov, Julie C., Larsen, Jesper, Heegaard, Niels H., Buschard, Karsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067331/ https://www.ncbi.nlm.nih.gov/pubmed/27795959 http://dx.doi.org/10.1155/2016/2424306 |
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