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Cox-2 Inhibition Protects against Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis via Akt-Dependent Enhancement of iNOS Expression

The present study explored the potential causal link between ischemia-driven cyclooxygenase-2 (COX-2) expression and enhanced apoptosis during myocardial ischemia/reperfusion (I/R) by using H9C2 cardiomyocytes and primary rat cardiomyocytes subjected to hypoxia/reoxygenation (H/R). The results showe...

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Detalles Bibliográficos
Autores principales:	Pang, Lei, Cai, Yin, Tang, Eva Hoi Ching, Yan, Dan, Kosuru, Ramoji, Li, Haobo, Irwin, Michael G., Ma, Haichun, Xia, Zhengyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067333/ https://www.ncbi.nlm.nih.gov/pubmed/27795807 http://dx.doi.org/10.1155/2016/3453059

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