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7,8-Dihydroxyflavone, a Tropomyosin-Kinase Related Receptor B Agonist, Produces Fast-Onset Antidepressant-Like Effects in Rats Exposed to Chronic Mild Stress

OBJECTIVE: Brain-derived neurotrophic factor (BDNF) and its specific receptor, tropomyosin-related kinase (TrkB), play important roles in treating depression. In this experiment, we examined whether 7,8-dihydroxyflavone, a novel potent TrkB agonist, could reverse the behavioral and biochemical abnor...

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Detalles Bibliográficos
Autores principales:	Chang, Hsin-An, Wang, Ying-Hsiu, Tung, Che-Se, Yeh, Chin-Bin, Liu, Yia-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Neuropsychiatric Association 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067348/ https://www.ncbi.nlm.nih.gov/pubmed/27757132 http://dx.doi.org/10.4306/pi.2016.13.5.531

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