Structural and haemostatic features of pharmaceutical heparins from different animal sources: challenges to define thresholds separating distinct drugs

Heparins extracted from different animal sources have been conventionally considered effective anticoagulant and antithrombotic agents despite of their pharmacological dissimilarities. We performed herein a systematic analysis on the physicochemical properties, disaccharide composition, in vitro ant...

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Detalles Bibliográficos
Autores principales: Tovar, Ana M. F., Santos, Gustavo R. C., Capillé, Nina V., Piquet, Adriana A., Glauser, Bianca F., Pereira, Mariana S., Vilanova, Eduardo, Mourão, Paulo A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067489/
https://www.ncbi.nlm.nih.gov/pubmed/27752111
http://dx.doi.org/10.1038/srep35619

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