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Co‐expression of the protease furin in Nicotiana benthamiana leads to efficient processing of latent transforming growth factor‐β1 into a biologically active protein
Transforming growth factor beta (TGF‐β) is a signalling molecule that plays a key role in developmental and immunological processes in mammals. Three TGF‐β isoforms exist in humans, and each isoform has unique therapeutic potential. Plants offer a platform for the production of recombinant proteins,...
Autores principales: | Wilbers, Ruud H. P., Westerhof, Lotte B., van Raaij, Debbie R., van Adrichem, Marloes, Prakasa, Andreas D., Lozano‐Torres, Jose L., Bakker, Jaap, Smant, Geert, Schots, Arjen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067602/ https://www.ncbi.nlm.nih.gov/pubmed/26834022 http://dx.doi.org/10.1111/pbi.12530 |
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