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A Nuclear Attack on Traumatic Brain Injury: Sequestration of Cell Death in the Nucleus

BACKGROUND: Exportin 1 (XPO1/CRM1) plays prominent roles in the regulation of nuclear protein export. Selective inhibitors of nuclear export (SINE) are small orally bioavailable molecules that serve as drug‐like inhibitors of XPO1, with potent anti‐cancer properties. Traumatic brain injury (TBI) pre...

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Detalles Bibliográficos
Autores principales: Tajiri, Naoki, De La Peña, Ike, Acosta, Sandra A., Kaneko, Yuji, Tamir, Sharon, Landesman, Yosef, Carlson, Robert, Shacham, Sharon, Borlongan, Cesar V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067638/
https://www.ncbi.nlm.nih.gov/pubmed/26842647
http://dx.doi.org/10.1111/cns.12501

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