αTAT1 controls longitudinal spreading of acetylation marks from open microtubules extremities

Acetylation of the lysine 40 of α-tubulin (K40) is a post-translational modification occurring in the lumen of microtubules (MTs) and is controlled by the α-tubulin acetyl-transferase αTAT1. How αTAT1 accesses the lumen and acetylates α-tubulin there has been an open question. Here, we report that a...

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Detalles Bibliográficos
Autores principales: Ly, Nathalie, Elkhatib, Nadia, Bresteau, Enzo, Piétrement, Olivier, Khaled, Mehdi, Magiera, Maria M., Janke, Carsten, Le Cam, Eric, Rutenberg, Andrew D., Montagnac, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067677/
https://www.ncbi.nlm.nih.gov/pubmed/27752143
http://dx.doi.org/10.1038/srep35624

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