Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti‐tau antibody AT8

Microtubule‐associated protein tau becomes abnormally phosphorylated in Alzheimer's disease and other tauopathies and forms aggregates of paired helical filaments (PHF‐tau). AT8 is a PHF‐tau‐specific monoclonal antibody that is a commonly used marker of neuropathology because of its recognition...

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Detalles Bibliográficos
Autores principales: Malia, Thomas J., Teplyakov, Alexey, Ernst, Robin, Wu, Sheng‐Jiun, Lacy, Eilyn R., Liu, Xuesong, Vandermeeren, Marc, Mercken, Marc, Luo, Jinquan, Sweet, Raymond W., Gilliland, Gary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067699/
https://www.ncbi.nlm.nih.gov/pubmed/26800003
http://dx.doi.org/10.1002/prot.24988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067699/
https://www.ncbi.nlm.nih.gov/pubmed/26800003
http://dx.doi.org/10.1002/prot.24988

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