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Significantly enhancing recombinant alkaline amylase production in Bacillus subtilis by integration of a novel mutagenesis-screening strategy with systems-level fermentation optimization
BACKGROUND: Alkaline amylase has significant potential for applications in the textile, paper and detergent industries, however, low yield of which cannot meet the requirement of industrial application. In this work, a novel ARTP mutagenesis-screening method and fermentation optimization strategies...
Autores principales: | Ma, Yingfang, Shen, Wei, Chen, Xianzhong, Liu, Long, Zhou, Zhemin, Xu, Fei, Yang, Haiquan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067897/ https://www.ncbi.nlm.nih.gov/pubmed/27777616 http://dx.doi.org/10.1186/s13036-016-0035-2 |
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