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5-Fluorouracil upregulates cell surface B7-H1 (PD-L1) expression in gastrointestinal cancers

BACKGROUND: Resistance to chemotherapy is a major obstacle in the effective treatment of cancer patients. B7-homolog 1, also known as programmed death ligand-1 (PD-L1), is an immunoregulatory protein that is overexpressed in several human cancers. Interaction of B7-H1 with programmed death 1 (PD-1)...

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Detalles Bibliográficos
Autores principales:	Van Der Kraak, Lauren, Goel, Gaurav, Ramanan, Krishnaveni, Kaltenmeier, Christof, Zhang, Lin, Normolle, Daniel P., Freeman, Gordon J., Tang, Daolin, Nason, Katie S., Davison, Jon M., Luketich, James D., Dhupar, Rajeev, Lotze, Michael T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067917/ https://www.ncbi.nlm.nih.gov/pubmed/27777774 http://dx.doi.org/10.1186/s40425-016-0163-8

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