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Controversies and evidence of hepatic resection for hepatocellular carcinoma()

Symptoms of early hepatocellular carcinoma (HCC) often go unnoticed, so more than half of patients with primary HCC are diagnosed after their disease has already reached an intermediate or advanced stage, or after portal hypertension has appeared. While hepatic resection is widely recognized as a fi...

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Autores principales: Zhong, Jian-Hong, Torzilli, Guido, Xing, Hao, Li, Chao, Han, Jun, Liang, Lei, Zhang, Han, Dai, Shu-Yang, Li, Le-Qun, Shen, Feng, Yang, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067978/
https://www.ncbi.nlm.nih.gov/pubmed/27761414
http://dx.doi.org/10.1016/j.bbacli.2016.10.001
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author Zhong, Jian-Hong
Torzilli, Guido
Xing, Hao
Li, Chao
Han, Jun
Liang, Lei
Zhang, Han
Dai, Shu-Yang
Li, Le-Qun
Shen, Feng
Yang, Tian
author_facet Zhong, Jian-Hong
Torzilli, Guido
Xing, Hao
Li, Chao
Han, Jun
Liang, Lei
Zhang, Han
Dai, Shu-Yang
Li, Le-Qun
Shen, Feng
Yang, Tian
author_sort Zhong, Jian-Hong
collection PubMed
description Symptoms of early hepatocellular carcinoma (HCC) often go unnoticed, so more than half of patients with primary HCC are diagnosed after their disease has already reached an intermediate or advanced stage, or after portal hypertension has appeared. While hepatic resection is widely recognized as a first-line therapy to treat very early or early HCC, its use in treating intermediate or advanced HCC or HCC involving portal hypertension remains controversial. Here we review PubMed-indexed literature covering the use of hepatic resection for such patients. The available evidence strongly suggests that, as a result of improvements in surgical techniques and perioperative care, hepatic resection can benefit many patients with intermediate or advanced HCC or with HCC associated with portal hypertension.
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spelling pubmed-50679782016-10-19 Controversies and evidence of hepatic resection for hepatocellular carcinoma() Zhong, Jian-Hong Torzilli, Guido Xing, Hao Li, Chao Han, Jun Liang, Lei Zhang, Han Dai, Shu-Yang Li, Le-Qun Shen, Feng Yang, Tian BBA Clin Review Article Symptoms of early hepatocellular carcinoma (HCC) often go unnoticed, so more than half of patients with primary HCC are diagnosed after their disease has already reached an intermediate or advanced stage, or after portal hypertension has appeared. While hepatic resection is widely recognized as a first-line therapy to treat very early or early HCC, its use in treating intermediate or advanced HCC or HCC involving portal hypertension remains controversial. Here we review PubMed-indexed literature covering the use of hepatic resection for such patients. The available evidence strongly suggests that, as a result of improvements in surgical techniques and perioperative care, hepatic resection can benefit many patients with intermediate or advanced HCC or with HCC associated with portal hypertension. Elsevier 2016-10-11 /pmc/articles/PMC5067978/ /pubmed/27761414 http://dx.doi.org/10.1016/j.bbacli.2016.10.001 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Zhong, Jian-Hong
Torzilli, Guido
Xing, Hao
Li, Chao
Han, Jun
Liang, Lei
Zhang, Han
Dai, Shu-Yang
Li, Le-Qun
Shen, Feng
Yang, Tian
Controversies and evidence of hepatic resection for hepatocellular carcinoma()
title Controversies and evidence of hepatic resection for hepatocellular carcinoma()
title_full Controversies and evidence of hepatic resection for hepatocellular carcinoma()
title_fullStr Controversies and evidence of hepatic resection for hepatocellular carcinoma()
title_full_unstemmed Controversies and evidence of hepatic resection for hepatocellular carcinoma()
title_short Controversies and evidence of hepatic resection for hepatocellular carcinoma()
title_sort controversies and evidence of hepatic resection for hepatocellular carcinoma()
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067978/
https://www.ncbi.nlm.nih.gov/pubmed/27761414
http://dx.doi.org/10.1016/j.bbacli.2016.10.001
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