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Human Cytochrome P450 Enzyme Modulation by Gymnema sylvestre: A Predictive Safety Evaluation by LC-MS/MS

BACKGROUND: Traditionally GS is used to treat diabetes mellitus. Drug-herb interaction of GS via cytochrome P450 enzyme system by substrate cocktail method using HLM has not been reported. OBJECTIVE: To evaluate the in-vitro modulatory effects of GS extracts (aqueous, methanol, ethyl acetate, chloro...

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Detalles Bibliográficos
Autores principales:	Rammohan, Bera, Samit, Karmakar, Chinmoy, Das, Arup, Saha, Amit, Kundu, Ratul, Sarkar, Sanmoy, Karmakar, Dipan, Adhikari, Tuhinadri, Sen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068113/ https://www.ncbi.nlm.nih.gov/pubmed/27761064 http://dx.doi.org/10.4103/0973-1296.191441

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