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Two different “tales” of ATG7: Clinical relevance to myelodysplastic syndromes
Somatic mutations in U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1) are associated with various cancers including myelodysplastic syndrome (MDS). Mutant U2AF1 promotes malignant transformation by inhibiting autophagy, partly as a result of alterations in the 3′ tail of ATG7. This results in altered...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068173/ https://www.ncbi.nlm.nih.gov/pubmed/27857975 http://dx.doi.org/10.1080/23723556.2016.1212686 |