Quantitative imaging for development of companion diagnostics to drugs targeting HGF/MET

The limited clinical success of anti‐HGF/MET drugs can be attributed to the lack of predictive biomarkers that adequately select patients for treatment. We demonstrate here that quantitative digital imaging of formalin fixed paraffin embedded tissues stained by immunohistochemistry can be used to me...

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Detalles Bibliográficos
Autores principales: Huang, Fangjin, Ma, Zhaoxuan, Pollan, Sara, Yuan, Xiaopu, Swartwood, Steven, Gertych, Arkadiusz, Rodriguez, Maria, Mallick, Jayati, Bhele, Sanica, Guindi, Maha, Dhall, Deepti, Walts, Ann E, Bose, Shikha, de Peralta Venturina, Mariza, Marchevsky, Alberto M, Luthringer, Daniel J, Feller, Stephan M, Berman, Benjamin, Freeman, Michael R, Alvord, W Gregory, Vande Woude, George, Amin, Mahul B, Knudsen, Beatrice S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068192/
https://www.ncbi.nlm.nih.gov/pubmed/27785366
http://dx.doi.org/10.1002/cjp2.49

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