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Progressive alterations in multipotent hematopoietic progenitors underlie lymphoid cell loss in aging

Declining immune function with age is associated with reduced lymphoid output of hematopoietic stem cells (HSCs). Currently, there is poor understanding of changes with age in the heterogeneous multipotent progenitor (MPP) cell compartment, which is long lived and responsible for dynamically regulat...

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Detalles Bibliográficos
Autores principales:	Young, Kira, Borikar, Sneha, Bell, Rebecca, Kuffler, Lauren, Philip, Vivek, Trowbridge, Jennifer J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068232/ https://www.ncbi.nlm.nih.gov/pubmed/27811054 http://dx.doi.org/10.1084/jem.20160168

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