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NFATC3 promotes IRF7 transcriptional activity in plasmacytoid dendritic cells
Plasmacytoid dendritic cells (pDCs) rapidly produce large amounts of type 1 interferon (IFN) after Toll-like receptor 7 and 9 engagements. This specialized function of type 1 IFN production is directly linked to the constitutive expression of IRF7, the master transcription factor for type 1 IFN prod...
Autores principales: | Bao, Musheng, Wang, York, Liu, Ying, Shi, Peiqing, Lu, Hongbo, Sha, Wenwen, Weng, Leiyun, Hanabuchi, Shino, Qin, Jun, Plumas, Joel, Chaperot, Laurence, Zhang, Zhiqiang, Liu, Yong-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068237/ https://www.ncbi.nlm.nih.gov/pubmed/27697837 http://dx.doi.org/10.1084/jem.20160438 |
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