Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library

The addition of palmitoyl moieties to proteins regulates their membrane targeting, subcellular localization, and stability. Dysregulation of the enzymes which catalyzed the palmitoyl addition and/or the substrates of these enzymes have been linked to cancer, cardiovascular, and neurological disorder...

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Detalles Bibliográficos
Autores principales: Hamel, Laura D., Lenhart, Brian J., Mitchell, David A., Santos, Radleigh G., Giulianotti, Marc A., Deschenes, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068503/
https://www.ncbi.nlm.nih.gov/pubmed/27009891
http://dx.doi.org/10.2174/1386207319666160324123844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068503/
https://www.ncbi.nlm.nih.gov/pubmed/27009891
http://dx.doi.org/10.2174/1386207319666160324123844

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