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NS1 Protein Mutation I64T Affects Interferon Responses and Virulence of Circulating H3N2 Human Influenza A Viruses

Influenza NS1 protein is the main viral protein counteracting host innate immune responses, allowing the virus to efficiently replicate in interferon (IFN)-competent systems. In this study, we analyzed NS1 protein variability within influenza A (IAV) H3N2 viruses infecting humans during the 2012-201...

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Detalles Bibliográficos
Autores principales:	DeDiego, Marta L., Nogales, Aitor, Lambert-Emo, Kris, Martinez-Sobrido, Luis, Topham, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068522/ https://www.ncbi.nlm.nih.gov/pubmed/27535054 http://dx.doi.org/10.1128/JVI.01039-16

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