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An Essential Role of INI1/hSNF5 Chromatin Remodeling Protein in HIV-1 Posttranscriptional Events and Gag/Gag-Pol Stability

INI1/hSNF5/SMARCB1/BAF47 is an HIV-specific integrase (IN)-binding protein that influences HIV-1 transcription and particle production. INI1 binds to SAP18 (Sin3a-associated protein, 18 kDa), and both INI1 and SAP18 are incorporated into HIV-1 virions. To determine the significance of INI1 and the I...

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Detalles Bibliográficos
Autores principales: La Porte, Annalena, Cano, Jennifer, Wu, Xuhong, Mitra, Doyel, Kalpana, Ganjam V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068538/
https://www.ncbi.nlm.nih.gov/pubmed/27558426
http://dx.doi.org/10.1128/JVI.00323-16