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Characterization of brain mGluR5 binding in a pilot study of late-life major depressive disorder using positron emission tomography and [(11)C]ABP688
The metabotropic glutamate receptor subtype 5 (mGluR5) has been implicated in the pathophysiology of mood and anxiety disorders and is a potential treatment target in major depressive disorder (MDD). This study compared brain mGluR5 binding in elderly patients suffering from MDD with that in elderly...
Autores principales: | DeLorenzo, C, Sovago, J, Gardus, J, Xu, J, Yang, J, Behrje, R, Kumar, J S D, Devanand, D P, Pelton, G H, Mathis, C A, Mason, N S, Gomez-Mancilla, B, Aizenstein, H, Mann, J J, Parsey, R V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068588/ https://www.ncbi.nlm.nih.gov/pubmed/26645628 http://dx.doi.org/10.1038/tp.2015.189 |
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