Cargando…
Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers
Precision genetic engineering accelerates the genetic improvement of livestock for agriculture and biomedicine. We have recently reported our success in producing gene-modified goats using the CRISPR/Cas9 system through microinjection of Cas9 mRNA and sgRNAs targeting the MSTN and FGF5 genes in goat...
Autores principales: | Wang, Xiaolong, Cai, Bei, Zhou, Jiankui, Zhu, Haijing, Niu, Yiyuan, Ma, Baohua, Yu, Honghao, Lei, Anmin, Yan, Hailong, Shen, Qiaoyan, Shi, Lei, Zhao, Xiaoe, Hua, Jinlian, Huang, Xingxu, Qu, Lei, Chen, Yulin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068700/ https://www.ncbi.nlm.nih.gov/pubmed/27755602 http://dx.doi.org/10.1371/journal.pone.0164640 |
Ejemplares similares
-
Correction: Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers
por: Wang, Xiaolong, et al.
Publicado: (2016) -
Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system
por: Wang, Xiaolong, et al.
Publicado: (2015) -
Multiplex gene editing via CRISPR/Cas9 exhibits desirable muscle hypertrophy without detectable off-target effects in sheep
por: Wang, Xiaolong, et al.
Publicado: (2016) -
Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats
por: Gao, Ye, et al.
Publicado: (2016) -
Discovery of cashmere goat (Capra hircus) microRNAs in skin and hair follicles by Solexa sequencing
por: Yuan, Chao, et al.
Publicado: (2013)