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Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers

Precision genetic engineering accelerates the genetic improvement of livestock for agriculture and biomedicine. We have recently reported our success in producing gene-modified goats using the CRISPR/Cas9 system through microinjection of Cas9 mRNA and sgRNAs targeting the MSTN and FGF5 genes in goat...

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Detalles Bibliográficos
Autores principales: Wang, Xiaolong, Cai, Bei, Zhou, Jiankui, Zhu, Haijing, Niu, Yiyuan, Ma, Baohua, Yu, Honghao, Lei, Anmin, Yan, Hailong, Shen, Qiaoyan, Shi, Lei, Zhao, Xiaoe, Hua, Jinlian, Huang, Xingxu, Qu, Lei, Chen, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068700/
https://www.ncbi.nlm.nih.gov/pubmed/27755602
http://dx.doi.org/10.1371/journal.pone.0164640

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