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The Ebola Virus VP30-NP Interaction Is a Regulator of Viral RNA Synthesis
Filoviruses are capable of causing deadly hemorrhagic fevers. All nonsegmented negative-sense RNA-virus nucleocapsids are composed of a nucleoprotein (NP), a phosphoprotein (VP35) and a polymerase (L). However, the VP30 RNA-synthesis co-factor is unique to the filoviruses. The assembly, structure, a...
Autores principales: | Kirchdoerfer, Robert N., Moyer, Crystal L., Abelson, Dafna M., Saphire, Erica Ollmann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068707/ https://www.ncbi.nlm.nih.gov/pubmed/27755595 http://dx.doi.org/10.1371/journal.ppat.1005937 |
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