Cargando…

Conveying Equipoise during Recruitment for Clinical Trials: Qualitative Synthesis of Clinicians’ Practices across Six Randomised Controlled Trials

BACKGROUND: Randomised controlled trials (RCTs) are essential for evidence-based medicine and increasingly rely on front-line clinicians to recruit eligible patients. Clinicians’ difficulties with negotiating equipoise is assumed to undermine recruitment, although these issues have not yet been empi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rooshenas, Leila, Elliott, Daisy, Wade, Julia, Jepson, Marcus, Paramasivan, Sangeetha, Strong, Sean, Wilson, Caroline, Beard, David, Blazeby, Jane M., Birtle, Alison, Halliday, Alison, Rogers, Chris A., Stein, Rob, Donovan, Jenny L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068710/ https://www.ncbi.nlm.nih.gov/pubmed/27755555 http://dx.doi.org/10.1371/journal.pmed.1002147

Ejemplares similares

Development of a framework to improve the process of recruitment to randomised controlled trials (RCTs): the SEAR (Screened, Eligible, Approached, Randomised) framework
por: Wilson, Caroline, et al.
Publicado: (2018)

An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment
por: Jepson, Marcus, et al.
Publicado: (2018)

Optimising recruitment and informed consent in randomised controlled trials: the development and implementation of the Quintet Recruitment Intervention (QRI)
por: Donovan, Jenny L., et al.
Publicado: (2016)

Equipoise in action: a qualitative investigation across six pragmatic randomised controlled trials (RCTs)
por: Rooshenas, Leila, et al.
Publicado: (2015)

The intellectual challenges and emotional consequences of equipoise contributed to the fragility of recruitment in six randomized controlled trials()
por: Donovan, Jenny L., et al.
Publicado: (2014)

Key issues in recruitment to randomised controlled trials with very different interventions: a qualitative investigation of recruitment to the SPARE trial (CRUK/07/011)
por: Paramasivan, Sangeetha, et al.
Publicado: (2011)

Understanding the perspectives of recruiters is key to improving randomised controlled trial enrolment: a qualitative evidence synthesis
por: Farrar, Nicola, et al.
Publicado: (2022)

Informed consent in randomised controlled trials: development and preliminary evaluation of a measure of Participatory and Informed Consent (PIC)
por: Wade, Julia, et al.
Publicado: (2017)

The QuinteT Recruitment Intervention supported five randomized trials to recruit to target: a mixed-methods evaluation
por: Rooshenas, Leila, et al.
Publicado: (2019)

Development of a new adapted QuinteT Recruitment Intervention (QRI-Two) for rapid application to RCTs underway with enrolment shortfalls—to identify previously hidden barriers and improve recruitment
por: Donovan, Jenny L., et al.
Publicado: (2022)

A simple technique to identify key recruitment issues in randomised controlled trials: Q-QAT - quanti-qualitative appointment timing
por: Paramasivan, Sangeetha, et al.
Publicado: (2013)

‘Keep an open mind’: using qualitative research to make recruitment easier in the by-band randomised controlled trial
por: Paramasivan, Sangeetha, et al.
Publicado: (2013)

Understanding the role of teamwork in recruitment to randomised controlled trials in surgical oncology-results from an exploratory study
por: Strong, Sean, et al.
Publicado: (2015)

‘The trial is owned by the team, not by an individual’: a qualitative study exploring the role of teamwork in recruitment to randomised controlled trials in surgical oncology
por: Strong, Sean, et al.
Publicado: (2016)

Recruiters’ perspectives and experiences of trial recruitment processes: a qualitative evidence synthesis protocol
por: Farrar, Nicola, et al.
Publicado: (2021)

A simple technique to identify key recruitment issues in randomised controlled trials: Q-QAT - quanti-qualitative appointment timing
por: Paramasivan, Sangeetha, et al.
Publicado: (2015)

Training health professionals to recruit into challenging randomized controlled trials improved confidence: the development of the QuinteT randomized controlled trial recruitment training intervention
por: Mills, Nicola, et al.
Publicado: (2018)

Training recruiters to randomized trials to facilitate recruitment and informed consent by exploring patients' treatment preferences
por: Mills, Nicola, et al.
Publicado: (2014)

Non-COVID-19 UK clinical trials and the COVID-19 pandemic: impact, challenges and possible solutions
por: Lorenc, Ava, et al.
Publicado: (2023)

Equipoise across the patient population: optimising recruitment to a randomised controlled trial
por: Whybrow, Paul, et al.
Publicado: (2017)

“It's what we call a randomised control trial” exploring how randomisation is presented by recruiters in RCTs
por: Jepson, Marcus, et al.
Publicado: (2015)

Evaluating best practice in informed consent discussions: a new method of evaluating information provision and patient understanding during trial recruitment consultations
por: Wade, Julia, et al.
Publicado: (2013)

Infectious Diseases Clinician's Variation in the Management of Pediatric Staphylococcus aureus Bacteraemia and Equipoise for Clinical Trials
por: Campbell, Anita J., et al.
Publicado: (2019)

Challenges of Recruiting Patients Into Group-Based Stroke Rehabilitation Research: Reflections on Clinician Equipoise Within the Singing for People With Aphasia (SPA) Pilot Trial
por: Calitri, Raff, et al.
Publicado: (2021)

Challenges Conveying Clinical Equipoise and Exploring Patient Treatment Preferences in an Oncology Trial Comparing Active Monitoring with Radiotherapy (ROAM/EORTC 1308)
por: Sherratt, Frances C., et al.
Publicado: (2020)

Clear obstacles and hidden challenges: understanding recruiter perspectives in six pragmatic randomised controlled trials
por: Donovan, Jenny L, et al.
Publicado: (2014)

‘Overnight, things changed. Suddenly, we were in it’: a qualitative study exploring how surgical teams mitigated risks of COVID-19
por: Elliott, Daisy, et al.
Publicado: (2021)

How pre-trial qualitative research can change proposed RCT design: a case study and implications for future research
por: Rooshenas, Leila, et al.
Publicado: (2015)

Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation vs radical prostatectomy for unilateral localised prostate cancer
por: Elliott, Daisy, et al.
Publicado: (2018)

What empirical research has been undertaken on the ethics of clinical research in India? A systematic scoping review and narrative synthesis
por: Paramasivan, Sangeetha, et al.
Publicado: (2021)

Integrating qualitative research in a multi-centre trial - the clinical trials unit perspective
por: Rogers, CA, et al.
Publicado: (2013)

Equipoise and the technology curve: Relevance in the design of Surgical trials
por: Simpson, A. H. R. W., et al.
Publicado: (2016)

Glycemic equipoise
por: Kalra, Sanjay, et al.
Publicado: (2017)

Detailed systematic analysis of recruitment strategies in randomised controlled trials in patients with an unscheduled admission to hospital
por: Rowlands, Ceri, et al.
Publicado: (2018)

A surplus of positive trials: weighing biases and reconsidering equipoise
por: Felson, David T, et al.
Publicado: (2004)

The challenge of equipoise in trials with a surgical and non-surgical comparison: a qualitative synthesis using meta-ethnography
por: Davies, Loretta, et al.
Publicado: (2021)

Enabling recruitment success in bariatric surgical trials: pilot phase of the By-Band-Sleeve study
por: Paramasivan, S, et al.
Publicado: (2017)

What to do with the equipoise?
por: Knol, Wiebe G, et al.
Publicado: (2019)

Strategies to Improve Recruitment to a De-escalation Trial: A Mixed-Methods Study of the OPTIMA Prelim Trial in Early Breast Cancer
por: Conefrey, C., et al.
Publicado: (2020)

‘Recruitment, recruitment, recruitment’ – the need for more focus on retention: a qualitative study of five trials
por: Daykin, Anne, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_p1p5tuu07rh4v13fkfq3gur626