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Modifications of the endosomal compartment in peripheral blood mononuclear cells and fibroblasts from Alzheimer's disease patients
Identification of blood-based biomarkers of Alzheimer's disease (AD) remains a challenge. Neuropathological studies have identified enlarged endosomes in post-mortem brains as the earliest cellular change associated to AD. Here the presence of enlarged endosomes was investigated in peripheral b...
Autores principales: | Corlier, F, Rivals, I, Lagarde, J, Hamelin, L, Corne, H, Dauphinot, L, Ando, K, Cossec, J-C, Fontaine, G, Dorothée, G, Malaplate-Armand, C, Olivier, J-L, Dubois, B, Bottlaender, M, Duyckaerts, C, Sarazin, M, Potier, M-C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068716/ https://www.ncbi.nlm.nih.gov/pubmed/26151923 http://dx.doi.org/10.1038/tp.2015.87 |
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