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Alterations in circadian entrainment precede the onset of depression-like behavior that does not respond to fluoxetine
Growing evidence links adverse prenatal conditions to mood disorders. We investigated the long-term behavioral alterations induced by prenatal exposure to excess glucocorticoids (dexamethasone—DEX). At 12 months, but not earlier, DEX-exposed mice displayed depression-like behavior and impaired hippo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068723/ https://www.ncbi.nlm.nih.gov/pubmed/26171984 http://dx.doi.org/10.1038/tp.2015.94 |