Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia

Genetic associations involving both rare and common alleles have been reported for schizophrenia but there have been no systematic scans for rare recessive genotypes using fully phased trio data. Here, we use exome sequencing in 604 schizophrenia proband–parent trios to investigate the role of reces...

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Detalles Bibliográficos
Autores principales: Rees, E, Kirov, G, Walters, J T, Richards, A L, Howrigan, D, Kavanagh, D H, Pocklington, A J, Fromer, M, Ruderfer, D M, Georgieva, L, Carrera, N, Gormley, P, Palta, P, Williams, H, Dwyer, S, Johnson, J S, Roussos, P, Barker, D D, Banks, E, Milanova, V, Rose, S A, Chambert, K, Mahajan, M, Scolnick, E M, Moran, J L, Tsuang, M T, Glatt, S J, Chen, W J, Hwu, H-G, Neale, B M, Palotie, A, Sklar, P, Purcell, S M, McCarroll, S A, Holmans, P, Owen, M J, O'Donovan, M C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068730/
https://www.ncbi.nlm.nih.gov/pubmed/26196440
http://dx.doi.org/10.1038/tp.2015.99

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