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An Abbreviated Protocol for In Vitro Generation of Functional Human Embryonic Stem Cell-Derived Beta-Like Cells
The ability to yield glucose-responsive pancreatic beta-cells from human pluripotent stem cells in vitro will facilitate the development of the cell replacement therapies for the treatment of Type 1 Diabetes. Here, through the sequential in vitro targeting of selected signaling pathways, we have dev...
Autores principales: | Massumi, Mohammad, Pourasgari, Farzaneh, Nalla, Amarnadh, Batchuluun, Battsetseg, Nagy, Kristina, Neely, Eric, Gull, Rida, Nagy, Andras, Wheeler, Michael B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068782/ https://www.ncbi.nlm.nih.gov/pubmed/27755557 http://dx.doi.org/10.1371/journal.pone.0164457 |
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