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R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects

Although the efficacy of racemate ketamine, a rapid onset and sustained antidepressant, for patients with treatment-resistant depression was a serendipitous finding, clinical use of ketamine is limited, due to psychotomimetic side effects and abuse liability. Behavioral and side-effect evaluation te...

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Detalles Bibliográficos
Autores principales: Yang, C, Shirayama, Y, Zhang, J-c, Ren, Q, Yao, W, Ma, M, Dong, C, Hashimoto, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068814/
https://www.ncbi.nlm.nih.gov/pubmed/26327690
http://dx.doi.org/10.1038/tp.2015.136