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Mms21 SUMO Ligase Activity Promotes Nucleolar Function in Saccharomyces cerevisiae

The budding yeast E3 SUMO ligase Mms21, also known as Nse2, is a component of the Smc5/6 complex, which regulates sister chromatid cohesion, DNA replication, and repair. Our study shows that the mms21RINGΔ mutant exhibits (1) reduced ribosomal RNA production; (2) nuclear accumulation of ribosomal pr...

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Detalles Bibliográficos
Autores principales:	Kim, Dong-Hwan, Harris, Bethany, Wang, Fei, Seidel, Chris, McCroskey, Scott, Gerton, Jennifer L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2016
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068852/ https://www.ncbi.nlm.nih.gov/pubmed/27510371 http://dx.doi.org/10.1534/genetics.115.181750

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