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Repeated Duplication of Argonaute2 Is Associated with Strong Selection and Testis Specialization in Drosophila

Argonaute2 (Ago2) is a rapidly evolving nuclease in the Drosophila melanogaster RNA interference (RNAi) pathway that targets viruses and transposable elements in somatic tissues. Here we reconstruct the history of Ago2 duplications across the D. obscura group and use patterns of gene expression to i...

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Detalles Bibliográficos
Autores principales: Lewis, Samuel H., Webster, Claire L., Salmela, Heli, Obbard, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068860/
https://www.ncbi.nlm.nih.gov/pubmed/27535930
http://dx.doi.org/10.1534/genetics.116.192336