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Characterization of a Novel MMS-Sensitive Allele of Schizosaccharomyces pombe mcm4(+)
The minichromosome maintenance (MCM) complex is the conserved helicase motor of the eukaryotic replication fork. Mutations in the Mcm4 subunit are associated with replication stress and double strand breaks in multiple systems. In this work, we characterize a new temperature-sensitive allele of Schi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068930/ https://www.ncbi.nlm.nih.gov/pubmed/27473316 http://dx.doi.org/10.1534/g3.116.033571 |