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Characterization of a Novel MMS-Sensitive Allele of Schizosaccharomyces pombe mcm4(+)

The minichromosome maintenance (MCM) complex is the conserved helicase motor of the eukaryotic replication fork. Mutations in the Mcm4 subunit are associated with replication stress and double strand breaks in multiple systems. In this work, we characterize a new temperature-sensitive allele of Schi...

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Detalles Bibliográficos
Autores principales: Ranatunga, Nimna S., Forsburg, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068930/
https://www.ncbi.nlm.nih.gov/pubmed/27473316
http://dx.doi.org/10.1534/g3.116.033571

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