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Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans
Macrophages are key players involved in numerous pathophysiological pathways and an in-depth characterization of their gene regulatory networks can help in better understanding how their dysfunction may impact on human diseases. We here conducted a cross-species network analysis of macrophage gene e...
Autores principales: | Codoni, Veronica, Blum, Yuna, Civelek, Mete, Proust, Carole, Franzén, Oscar, Björkegren, Johan L. M., Le Goff, Wilfried, Cambien, Francois, Lusis, Aldons J., Trégouët, David-Alexandre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068955/ https://www.ncbi.nlm.nih.gov/pubmed/27558669 http://dx.doi.org/10.1534/g3.116.033894 |
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