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Characterization of a Thermostable 8-Oxoguanine DNA Glycosylase Specific for GO/N Mismatches from the Thermoacidophilic Archaeon Thermoplasma volcanium

The oxidation of guanine (G) to 7,8-dihydro-8-oxoguanine (GO) forms one of the major DNA lesions generated by reactive oxygen species (ROS). The GO can be corrected by GO DNA glycosylases (Ogg), enzymes involved in base excision repair (BER). Unrepaired GO induces mismatched base pairing with adenin...

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Detalles Bibliográficos
Autores principales:	Fujii, Miki, Hata, Chieri, Ukita, Munetada, Fukushima, Chie, Matsuura, Chihiro, Kawashima-Ohya, Yoshie, Tomobe, Koji, Kawashima, Tsuyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069365/ https://www.ncbi.nlm.nih.gov/pubmed/27799846 http://dx.doi.org/10.1155/2016/8734894

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